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In addition to its in vitro senolytic activity, ABT-263 has been shown to rejuvenate aged hematopoietic stem cells and effectively clear senescent cells in irradiated or aged mice (63)
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This was the first large-scale MR analysis that systematically assessed the causal relationship between circulating antioxidants and multiple cancer risks, utilizing summary data from GWAS studies containing 193,673 solid tumor cases and controls
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