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Description
Chitosan and its derivatives have also demonstrated significant advantages in nasal drug delivery by enhancing residence time through strong mucoadhesion while simultaneously promoting epithelial interaction and transient opening of tight junctions, thereby facilitating drug absorption without relying solely on high bulk viscosity (Casettari and Illum, 2014)

These regulatory effects may underlie observed improvements in sleep-wake patterns and neuroendocrine homeostasis in aged subjects [3]

Transgenerational neuroendocrine disruption of reproduction

doi: 10.1002/ibd.20930 259 JangSEHyamSRHanMJKimSYLeeBGKimDH
