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The postischemic GABA level restoration did not achieve the level before ischemia in 72 h reperfusion, which could be one of the limiting factors in the complete postischemic GABA transmission recovery
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This review examines the complex mechanisms underlying MTX-induced liver damage, including oxidative stress, mitochondrial impairment, inflammatory signaling pathways such as NF-B and JAK/STAT, and apoptosis
