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Lipovac, M., Nairz, V., Aschauer, J

VMAT1 is expressed in peripheral neuroendocrine cells (adrenal chromaffin cells, interneurons of sympathetic ganglia, and enterochromaffin cells that store serotonin in the GI tract)

By stimulating muscarinic receptors and producing a pinhole effect that can increase depth of field at all distances, pupil-constricting drugs, like 1.25% pilocarpine, promote accommodation [254]

Nanoscale delivery systems, such as polymer-drug nanoparticles, micelles, and liposomes, are being developed to increase their bioavailability and improve drug stability, which will improve the therapeutic efficacy