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168 In addition, KBs may regulate the homeostatic status of mitochondria by modulating calcium-induced membrane permeability transition

Although primarily recognized for its role in allergic reactions and inflammation, histamine can also display anti-inflammatory properties through mechanisms such as inhibition of IgE-mediated histamine release from peripheral leukocytes, suppression of neutrophil lysosomal enzyme release, and activation of suppressor T-lymphocytes 39