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It is warm to the touch and will last for about 3 days

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B12 vitamin shots begin working right away and your body will begin to manufacture new red blood cells as early as 48 hours

Call 911 immediately if you notice these signs of anaphylaxis after an injection: A sudden rash or hives Trouble breathing, wheezing Dizziness, fainting, or feeling weak Swelling of the face, lips, or tongue Fast or irregular heartbeat Nausea, vomiting, or diarrhea Trouble swallowing Cold, pale, or sweaty skin A strong sense that something is very wrong Anaphylaxis usually happens within 30 minutes, but in some cases, symptoms might be delayed for hours