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Rapid injection increases discomfort and may cause the medication to leak back out of the injection site

demonstrated that puerarin enhances antiPD-L1 efficacy by suppressing ROS production, thereby reducing CAF-mediated physical barriers, increasing T-cell infiltration, and alleviating immunosuppression in the tumor microenvironment (150)

Acknowledgements This project was funded by Research Ireland funding grant 20/FFP-A/8924

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