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At endpoint A, when compared with the CTRL group, no changes were found in the percentage of methylation of any of the evaluated positions in the cultures of MOD patients, while SEV patients had an hypomethylated CpG at chr17: 36,090,102 ( Figure 4 )
While semaglutide does not require dose adjustment for mild to moderate renal impairment, experience in patients with severe renal impairment is limited
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