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When at least 10 studies were available for each treatment against placebo, publication bias and small-study effects were examined visually using the comparison adjusted funnel plot under the fixed-effect model.3 When a funnel plot asymmetry was detected, we performed the Copas selection for the treatment comparisons that were informed by at least 10 studies and for which asymmetry was evident in the funnel plot

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These flavonoids are found in high concentrations in cocoa, but they are also present in smaller amounts in other plant-derived foods

executive dysfunction, which can include problems with planning, cognitive flexibility, abstract thinking, rule acquisition, initiating appropriate actions and inhibiting inappropriate actions, and selecting relevant sensoiy information, fluctuations in attention and slowed cognitive speed, memory (especially in recalling learned information), visuospatial difficulties e.g