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The DOPAL-modified -syn protein can accumulate in the endo-lysosomal pathway, leading to impaired proteostasis and neurodegeneration of dopaminergic neurons both in vitro and in vivo [69]

Nat Cell Biol (2008) 10(5):6118

225 This delay in muscular activation increases the window of time during which the ACL is vulnerable to excessive loading, making it more susceptible to ruptur

54 Dierkes, J