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However, this possibility remains to be investigated
doi:10.1002/cld.562 [PubMed][CrossRef] 3
Different GlyT1 inhibitors have been synthesized and assessed in preclinical models
However, in a more recent randomized, placebo-controlled study in 102 subjects, daily supplementation with 600 mg of lipoic acid (+/- 800 mg of vitamin E [-tocopherol]) for 16 weeks had no effect on fasting blood glucose, fasting blood insulin, or a measure of insulin resistance called the homeostatic model assessment of insulin resistance (HOMA-IR) index (59)
