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For example, chondrocytes isolated from OA cartilage displayed significant senescence levels, and ABT263 treatment reduced the expression of inflammatory cytokines and promoted cartilage matrix aggregation in OA chondrocytes (Yang et al., 2020)

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Laboratory animals were housed in polycarbonate (PC) cages under conventional laboratory conditions at 2024C, relative humidity of 4070%, and noise level of 60 dB