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doi: 10.3389/fcimb.2017.00455
Investigation of Clozapine and Olanzapine Reactive Metabolite Formation and Protein Binding by Liquid Chromatography-Tandem Mass Spectrometry
(2017) 152(6):144961.e7
In mitochondria, THF is imported via a mitochondrial folate transporter and converted into 5,10-methylene-THF by serine hydroxymethyltransferase 2 (SHMT2), which oxidizes serine to glycine while transferring a one-carbon unit to THF [15]
