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The IL-1R1-dependent response thus appears to reveal a damage-specific reparative capacity, which opens the door to IL-1-based therapeutic approaches (206)

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This deficit correlates with disease activity, suggesting that reduced thymosin alpha-1 may contribute to the immune dysregulation seen in SLE

Practical reality: for deep injuries (like a shoulder rotator cuff) or post-surgical patients with limited mobility, a standard sub-Q injection in the abdomen is a reasonable and functional alternative
