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MSC-like cells isolated from peripheral blood of osteoporotic patients with intervention with bisphosphonates showed significantly increased expression levels of the osteoblast marker gene Runt-associated transcription factor 2 (RUNX2) , BMP-2 and bone turnover markers C-terminal telopeptide (CTX), pre-collagen type 1 N-terminal pro-peptide (P1NP) and bone alkaline phosphatase (bALP) levels were significantly reduced (Dalle Carbonare et al., 2017

Recent large-scale phosphoproteomic studies have provided even more insight into the intricacies of the HGF/c-MET signaling axis [Organ et al

doi: 10.3390/jpm12050673, 188

Rather than working with multiple separate compounds, researchers can evaluate a single, consistent formulation, helping improve efficiency and reduce variability during experimental setup