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In cell culture studies, the knockdown of specific enzymes that synthesize GSH did cause both a decrease in GSH and the VD metabolism genes statuses, and L-cysteine supplementation simultaneously caused an improvement in both GSH and VD metabolism genes [3]

Surprisingly, no changes were reported in GSTA3, GSTA5, and GSTM1 mRNA levels (Yu et al

Moreover, GHK exhibits potent cell-protective actions, including anti-cancer and anti-inflammatory effects, lung protection, and restoration of chronic obstructive pulmonary disease (COPD) fibroblasts

Recently, it has been found that GPX1 is induced by etoposide, a topoisomerase II inhibitor, an apoptosis inducer and a p53 activator