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Methionine synthase A2756G polymorphism and breast cancer risk: A meta-analysis involving 18,953 subjects

It can also cause bruising

Across the six published trials, the most common adverse events were headache, mild gastrointestinal effects (diarrhea, flatulence, nausea), nasopharyngitis, fatigue, dizziness, and mild injection-site reactions

This is true for both oral supplements and injections, backed by clinical evidence