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Surprisingly, the mitochondrial stress response induced by ISC synthesis inhibition is not accompanied by upregulation and secretion of the metabokines GDF15 and FGF21, which mediate an adaptive response to mitochondrial dysfunction

No sedative effects were observed on any measure, no cognitive impairment was detected on neuropsychological testing, and no withdrawal symptoms occurred after discontinuation

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This is unusual breadth for a tripeptide
