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The epigenome is, indeed, influenced by metabolic factors (intracellular flux or availability of metabolites, drugs, eating habits and metabolic fitness) and environmental parameters in the strict sense (presence of pollutants, social relationships, mental and relational stress) 10

KLOW is research-use-only

Frontiers in Oncology , 14 , 1499125

The highly reactive oxygen radicals either decay spontaneously or are converted by superoxide dismutase to hydrogen peroxide (H 2 O 2 ), which is still highly toxic