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In contrast, serum ELISA antibody tests detect only immune sensitization, indirect evidence that cannot confirm current or ongoing exposure, and they lack validation for exposure assessment

However, not every type of probiotics exhibits the same effects in the organism, and to obtain the optimal immunostimulatory results, probiotics should be selected thoughtfully based on the clinical state of the disease (113)
This enables the acquisition of cellular functional and ultrastructural information with high specificity and resolution, thereby facilitating the localization of intratumoral bacteria
