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Serum trace metal levels in Alzheimers disease and normal control groups

According to evidence from post-mortem studies on patients with Parkinson's disease, synaptically coupled networks allow LP to spread from either the olfactory bulb or the dorsal motor nucleus of the vagus (DMV) in the caudal medulla to the substantia nigra pars compacta (SNpc) during the preclinical stages of the disease

The skin accounts for 16% of the total body weight and thanks to its continuous self-renewal activity, it is also a metabolically active organ that participates in the maintenance of homeostasis [1, 2]

At the end of all incubations, the hECs were washed three times with ice-cold PBS containing 0.1% BSA, once with acid stripping buffer (glycine 50 mM, NaCl 100 mM, pH 3) to remove the non-internalized, but cell surface-attached nanocarriers, and finally with PBS