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HUBERMAN: In order to find out the lethal dose of something, as you can imagine, unfortunately, the way these studies are done is they give animals more and more, that is higher and higher doses of a given compound, find out at what point about 50% of the population of those animals starts to die, and then that's the so-called LD50, or at least that's one crude way of describing it

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Rapid weight loss, extended undernutrition or extreme calorie reduction can stop typical steroidogenesis and cause follicle pools to diminish and eggs to fail to mature

Those who are dehydrated may find the blood draw portion more difficult