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[DOI] 148.Jani S, et al

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Originally developed to help patients manage type 2 diabetes, semaglutide gained widespread attention when studies showed it could help individuals lose a significant amount of weight by reducing hunger, slowing gastric emptying, and helping people feel full for longer periods

In humans this transition occurs from the zygote stage through the 8-cell stage, with major zygotic genome activation at the 4 to 8 cell stage [383, 384]