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Ursini and Maiorino, 2020) (Figure 4)

For the complete program registry, see ClinicalTrials.gov

A history of preterm birth, both with and without a history of BPD, has been consistently associated with poorer lung function in later life 4 , and there is growing evidence that those with a history of BPD risk the development of chronic obstructive pulmonary disease (COPD) in early adulthood 5, 6 , as well as being diagnosed with asthma 7 , although there is increasing recognition that prematurity-associated lung disease (PLD) has different underlying mechanism to asthma 8