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Description
This is a stable cellular line derivative from PLB-985 that lacks the gp91 phox subunit of the NADPH oxidase 2 (Nox2), because the gp91 phox gene was knocked out [22], which present a reduction of 3 times in the intracellular ROS levels [8]
Due to their small size and hydrophobic surface, GPX4s have the ability to react with complex lipids in membranes (19)
2021;75:S28990
elegans from stress via the SKN-1/NRF-2 pathway
