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In addition, ongoing research efforts are exploring the potential of MOR202 for treating membranous nephropathy (NCT04145440), while TAK79 is being investigated for conditions like severe systemic lupus erythematosus and myasthenia gravis (NCT04159805)

These sirtuins help preserve collagen by stopping MMP-1 gene transcription that breaks down collagen

10.1016/j.tcb.2014.04.002 [DOI] [PMC free article] [PubMed] [Google Scholar] 10.Verdin E

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