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Hypothyroidism: Effects of Vitamin D and B12 Deficiency Learn how vitamin D and B12 deficiencies exacerbate hypothyroidism

Sep 2024;91(5):105714

Aging Ment Health

First, FOXO4 localizes predominantly in the cytoplasm of normal Leydig cells, as shown by both our in vitro and in vivo findings, while it is within the nucleus that FOXO4-DRI interferes with the FOXO4-p53 interaction [24]
