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Caution Persons living in areas of high soil selenium, such as the Dakotas, should consult a healthcare practitioner prior to use

CYP isoforms not only metabolize many endogenous substances including prostaglandins, lipids, fatty acids, and steroid hormones but also metabolize (detoxify) exogenous substances including drugs Major CYP isoforms responsible for drug metabolism include: CYP3A4, CYP2D6, CYP2C9, CYP2C19, CYP1A2, CYP2E1 in in certain cases CYP2A6 and CYP2D6 Important enzymes for phase II reactions include: Glutathione-S-transferases UDP-glucuronosyl transferases Sulfotransferases N-acetyltransferases Methyltransferases and Acyltransferases

Archived from the original on 25 May 2025

F.2008Structure, function and polymorphism of human cytosolic sulfotransferases.92(February 2008),99105,1389-2002 73