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A comprehensive meta-analysis of 37 randomized controlled trials involving 2,292 participants found that L-Carnitine supplementation significantly decreased body weight by 1.21 kg, body mass index (BMI) by 0.24 kg/m, and fat mass by 2.08 kg compared to placebo

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Those with lower levels of folate are more likely to experience depression and less likely to respond to antidepressant medications