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Fertil Steril (2016) 106:158899

Several studies have found that people with high levels of homocysteine in their blood are at an increased risk of heart attack, stroke, and other cardiovascular events

2001;131(3s):1041S-1045S

For example, one study revealed that an overexpression of GPX1 inhibited the nucleus-translocation of apoptosis-inducing factor (AIF) from mitochondria in neuronal cells after ischemia-induced apoptosis (Zemlyak et al., 2009), another analysis showed that GPX1 decreased the ratio of Bax:Bcl-2 to create a more antiapoptotic environment in human endothelial cells ( Finally, we explored the possible signaling pathways by which GPX1 was involved in protecting SGNs against peroxynitrite-induced injury