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Biomedicines 2, 345358
Another study demonstrated pharmacological conditioning for JIA as a potential solution to reduce MTX intolerance [56]
Yang and co-workers reported a nanomedicine composed of dendritic mesoporous silica nanoparticles (DMSNs), Fe 3 O 4 , Mn, and glutaminase inhibitor Telaglenastat (CB-839) (termed DFMC) for restored oxaliplatin chemosensitivity on the basis of the GSH-responsive and -exhausting effect (Figure 4C) (Figure 4D)
The contribution of these alleles toward GSH homeostasis pathologies remains unclear
