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Trazodone, for example, metabolizes to mCPP, a BZP analogue that is significantly more harmful than straight-up BZP
Rapid acidification is required to prevent GSH auto-oxidation, GSH and GSSG degradation, as well as to precipitate proteins that interfere with analysis
This rapid clearance may help prevent the toxic accumulation of mediators in the bloodstream, significantly reducing the severity and duration of systemic MCAS flares, such as flushing, gastrointestinal distress, and neurological inflammation
He Y, Wang W, Yang T, Thomas ER, Dai R, Li X
