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In the midst of his career he developed an addiction to Vicodin (an analgesic medication that contains hydrocodone, an agonist of opiate receptors)

10.1016/j.bbadis.2016.03.010 Biochim

Nat Med 23:850858 Sun L, Xie C, Wang G, Wu Y, Wu Q, Wang X, Liu J, Deng Y, Xia J, Chen B, Zhang S, Yun C, Lian G, Zhang X, Zhang H, Bisson WH, Shi J, Gao X, Ge P, Liu C, Krausz KW, Nichols RG, Cai J, Rimal B, Patterson AD, Wang X, Gonzalez FJ, Jiang C (2018) Gut microbiota and intestinal FXR mediate the clinical benefits of metformin
