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Since 2017, the National Institute for Health and Care Excellence (NICE) has recommended that all people with colorectal cancer are tested for Lynch syndrome using Immunohistochemistry (IHC) or Microsatellite Instability (MSI) testing (DG27)

However, under pathological stressors such as chronic inflammation or oxidative stress, -synuclein undergoes conformational rearrangement: -helices destabilize, enabling transition into -sheet-rich oligomers 47,48

Research shows that vitamin E plays a key role in supporting cell health and survival by helping to regulate inflammation and activating important pathways that help with its absorption, transport, and use in the body