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If it was there would be signs of tolerance by the time but the neurogenic effect takes place over time

Vitamin E (a-tocopherol) is a fat-soluble antioxidant that can protect the polyunsaturated fatty acids (PUFAs) in the membrane from oxidation, regulate the production of ROS, and modulate signal transduction [24]

Recent research has shown that the uncoupling of eNOS in the penis also plays a major role in causing ED and regional oxidative stress [78]

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