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Studies have shown that all these drugs are not only good antioxidants, but also have a strong anti-inflammatory effect via Nrf2 induction in in vivo and/or in vitro experiments in periodontitis models

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Regulatory Steps of the HMP Shunt and Their Regulatory Factors The regulation of the HMP Shunt primarily occurs at the initial, irreversible steps of the oxidative phase, with the activity of Glucose-6-phosphate Dehydrogenase (G6PD) being the dominant control point