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NAFLD-associated chronic low-grade inflammation responds to L-carnitine supplementation through reduced hepatic pro-inflammatory cytokines (e.g., IL-6), increased anti-inflammatory cytokine IL-10, and downregulation of key inflammatory pathway components (TLR4, NF-B, JNK) ( NF-B represents a master regulator of inflammatory responses in NAFLD progression

According to data from the Cochrane review, administration of carnitines and combined AOX formulations had positive effect of sperm motility, and supplementation with polyunsaturated fats and zinc resulted in increase of sperm concentration (16)