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NCT05929079 Jastreboff AM, et al

Enzymes such as glutamate dehydrogenase replenish TCA intermediates and provide glutamate for GSH synthesis

Our present agents, such as allopurinol and probenecid, are so effective, and reasonably safe and predictable, that it seems unlikely that they will be fully displaced in the future

Cellular, molecular and functional characterisation of YAC transgenic mouse models of Friedreich ataxia
