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However, this reaction depends on the di-anion form which is only substantially abundant at very high pH [8]

By establishing a mouse model of whole-body irradiation using 8 Gy of 137 Cs- rays, Alis team found that RES pretreatment significantly inhibited radiation-induced inflammatory responses and cell apoptosis

10.3389/fcell.2022.849985 Front Cell Developmental Biol

Together, these results suggest that a moderate level of ferroptosis signaling promotes axonal fusion, while excessive ferroptosis signaling leads to axonal debris, possibly due to ferroptosis-induced axon degeneration
