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Description
Glycyrrhizin has been shown to inhibit complement activation by directly interfering with C2 cleavage and downstream C3 convertase formation, thereby reducing C4a generation

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It is believed that REM sleep dysregulation symptoms arise from the sporadic activation of REM sleep-promoting neurons during wakefulness, which causes REM sleep manifestationslike cataplexyto intrude into wakefulness (Thorpy & Bogan, 2020)
Following ONI, NO may similarly participate in retrograde injury signaling and the remodeling of synaptic signals
