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[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Chobanyan-Jrgens K., Jordan J

In the phase III trial, AVP-825 showed an earlier onset and consistent responses across multiple migraine attacks compared with 100 mg oral sumatriptan, supporting the clinical value of breath-driven delivery designed to improve deposition beyond the nasal valve (Lipton et al., 2017
While oral supplementation can be beneficial, it may not be as effective as direct administration methods

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