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Complete supply calculation for a 16-week protocol Weeks 1-4 (2mg/week): 2mg x 4 weeks = 8mg total Weeks 5-8 (4mg/week): 4mg x 4 weeks = 16mg total Weeks 9-12 (8mg/week): 8mg x 4 weeks = 32mg total Weeks 13-16 (12mg/week): 12mg x 4 weeks = 48mg total Grand total: 104mg over 16 weeks Now translate that into vials: Using 10mg vials exclusively: 104mg / 10mg = 10.4 vials

Comparison of the protective level in mild and severe infection We also tested if the protective neutralization level was different between mild and severe infection by fitting the combined dataset with two different mathematical models

Never change the dose or frequency without consulting the prescribing healthcare provider

4.4 Pharmacokinetic parameters in beagle dogs after intravenous and intramuscular administration Inthispartoftheexperiment,threemaleandthreefemale beagles were examined for four cycles