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Freezing the vial destroys it, and letting it warm above 10C accelerates degradation
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Its small size and copper-binding affinity underpin its bioactivity, distinguishing it from larger proteins or synthetic peptides

Gounder, M.D., of Memorial Sloan Kettering Cancer Center, who led the study

Notably, vagotomy experiments demonstrate that interrupting this pathway effectively blocks the spread of PD pathology from gut to brain [133]
