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This depends on how severe the deficiency is, any health conditions, and how well the therapy works

By blocking NNMT, it prevents the methylation reaction that depletes SAM and nicotinamide, thereby preserving both cofactors and restoring the metabolic machinery that NNMT overexpression had suppressed

The ultimate goal is to generate clinical evidence that leads to official changes in treatment guidelines, ensuring that injection frequency is based on patient-reported symptoms and individual clinical response, rather than solely on national blanket protocols

GHK-Cu works through cumulative tissue exposure, not peak concentration