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Clinical studies support this: exposure to diesel exhaust particles (DEPs) reduces peroxisomal ACOX1 expression in bronchial epithelial cells from asthma patients (105), exacerbating PUFA accumulation and ferroptosis
With 5 days of deferoxamine (an iron chelator) treatment, neuroblastoma regressions were observed in 7 of 9 patients at the dose of 150 mg/kg/day with an 8-h i.v
