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While Hashimotos is the leading cause, other factors like iodine deficiency or certain medications can also contribute
10.1016/j.mce.2017.09.016 108 TubbsE.TheureyP.VialG.BendridiN.BravardA.ChauvinM
doi: 10.1371/journal.pone.0123344
Notably, chronic exposure of chemotherapy agents enables to induce PKM2 expression via different mechanisms (Calabretta et al., 2016
