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1, there are two pathways for intracellular ROS production: nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) and mitochondrial involvement in metabolism [62]
doi: 10.1016/j.jprot.2014.03.021
2014 doi: 10.1016/j.biopsych.2014.10.021
The low sequence homology (4060%) among the five receptors explains the lack of ligand selectivity [13,14,15,16]
