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This selectivity was observed in animal models and has not been fully established in long-term human studies
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Muscogiuri G, Altieri B, de Angelis C, Palomba S, Pivonello R, Colao A

Impaired system Xc activity has been linked to xCT subunit inactivation (148), which sustains glutamate excitotoxicity in rat models of cerebral ischemia (149)

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