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[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Schwartz J., Evers A.W., Bundy C., Kimball A.B

Consistent with this, the multifunctional redox-sensitive protein DJ-1 (also known as PARK7) was shown to protect retinal ganglion cells from high glucose-induced oxidative stress by restoring MnSOD expression and activity, thereby maintaining mitochondrial membrane potential and promoting neuronal survival [81]

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Each modality targets pigment through a distinct biochemical pathway, which is why an accurate skin type assessment and thorough medical history review are prerequisites for safer outcomes and more effective results regardless of whether treatment is applied to the face or anywhere on the body