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Normally, IL-1 triggers rapid IB- degradation within 20 minutes, releasing NF-B to enter the nucleus

Apart from these systems, there are various cellular molecules which act as active antioxidants in our body like GSH, ascorbate (vitamin C), a-tocopherol (vitamin E), -carotene, NADPH, uric acid, bilirubin, sodium selenite, mannitol, sodium benzoate, the iron-binding protein transferrin, dihydrolipoic acid, melatonin, plasma protein thiol, and reduced CoQ10 which are involved in protecting the body from ROS and their byproducts produced during normal cellular metabolism [82]

In the present study, a subgroup analysis was used to identify the source of heterogeneity surrounding UPDRS and to perform in-depth data mining

Nutraceuticals in Health and Disease Prevention